Dorothy Kilgallen’s official cause of death was an acute combination of alcohol and barbiturates in her Manhattan townhouse on November 8, 1965, and authorities did not classify it as a clear suicide or homicide but left the manner of death “undetermined,” suggesting it could have been an accidental overdose.wikipedia+1

What is firmly established

Why her death became “mysterious”

Competing explanations

ExplanationMain claimSupporting pointsMain problems
Accidental overdoseShe unintentionally mixed too much alcohol and barbiturates.She had a history of heavy work, stress, and some prior issues with alcohol and pills; the official autopsy found enough barbiturate in her system to be lethal.wikipedia+1Unusual bedroom and clothing, missing notes, and her upbeat mood earlier that evening are hard to reconcile for some witnesses.arapahoenews+2
SuicideShe intentionally took a fatal dose.The large amount of barbiturates present and the pressures in her personal and professional life have led some to speculate about self-harm.reddit+1Police at the time said there was no indication of suicide, and friends insisted she seemed energized and future‑oriented, planning further JFK work and travel.arapahoenews+2
Homicide linked to her JFK workShe was killed—often alleged by being secretly given extra barbiturates—because she had uncovered sensitive information on the JFK assassination.Authors such as Mark Shaw argue her drink was spiked by an associate (often named as columnist Ron Pataky), possibly tied to intelligence or organized crime; they point to missing JFK files, FBI surveillance, and reports of agents or men removing documents from her home after her death.bridges.overdrive+2YouTubeThese claims rely heavily on later testimony, inference, and circumstantial links; there has been no official finding of homicide, and no one has been charged.digitalcommons.law.uga+1

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